Juleb Blog / How to Connect the Pharmacy Software to the E-Invoicing System Approved by zatca

How to Connect the Pharmacy Software to the E-Invoicing System Approved by zatca

The Kingdom of Saudi Arabia is undergoing a wide-ranging digital transformation across various sectors, most notably the healthcare sector and pharmaceutical retail. The ZATCA (Zakat, Tax and Customs Authority) has mandated the implementation of the e-invoicing system

This system aims to enhance transparency, combat commercial concealment, and improve operational efficiency within establishments. Pharmacies are among the entities subject to this mandate, requiring owners to connect their systems to ZATCA using reliable technical solutions.

That’s why it's essential to understand the practical steps of integrating your pharmacy software with the e-invoicing system , and to choose the right solution such as Juleb, which is fully compliant with ZATCA requirements.

1. What Is an E-Invoice and Why Does It Matter?

An e-invoice is a digital document created and stored electronically using a certified e-invoicing system. It differs from paper or manual invoices in format, content, transmission, and review methods.

Key Benefits of E-Invoicing:

  • Accurate documentation of commercial transactions

  • Reduction in tax fraud and manipulation

  • Faster financial processing

  • Simplified audit and data submission

  • Direct integration with government systems

  • ZATCA has divided the implementation into two main phases:

Phase 1: Invoice issuance and storage

Phase 2: Integration with ZATCA’s systems

2. Who Is Required to Comply with E-Invoicing?

E-invoicing

applies to all VAT-registered entities, including pharmacy owners. This includes independent pharmacies, pharmacy chains, and in-hospital pharmacies.

3. ZATCA Requirements for Pharmacy System Integration

To successfully connect your pharmacy software to the e-invoicing system, several technical and regulatory conditions must be met:

The system must be capable of:

  • Issuing invoices in XML or PDF/A-3 with embedded XML

  • Adding a QR code

  • Generating a UUID for each invoice

  • Maintaining a digital archive of invoices

  • Connecting via secure APIs or protocols with ZATCA

  • Real-time invoice issuance at the point of sale

  • Complying with ongoing ZATCA updates

4. Steps to Integrate Your Pharmacy Software with ZATCA

Step 1: Choose a Certified Software

Ensure your pharmacy software is ZATCA-approved and meets the technical standards. It's best to choose a comprehensive system that manages sales, inventory, financial reporting, and e-invoicing in one place for easier management and full integration.

Step 2: Configure the Settings

After selecting the software:

  • Enter all business and tax information (VAT number, commercial registration, etc.)

  • Activate the e-invoicing feature

  • Choose the invoice type (Standard or Simplified)

  • Set user permissions based on roles

Step 3: Connect the Software to ZATCA

After registering on the e-invoicing portal:

  • ZATCA will issue API credentials for integration

  • These credentials are added to your software

  • A preliminary test is conducted to ensure invoices are received successfully by ZATCA

Step 4: Test the Integration

Before going live: Send several test invoices

Monitor the response: Are invoices accepted? Are there data errors?

Ensure the system auto-sends invoices once issued

Step 5: Train Your Team

Your staff must be trained on:

How to issue electronic invoices

Handling special cases (cancellations, edits, returns)

Monitoring integration reports and checking invoice status

5. Why Is Juleb the Best Solution for Pharmacies?

Juleb is a comprehensive pharmacy management software offering end-to-end solutions for sales, inventory, invoicing, and accounting fully compliant with Saudi Arabia’s e-invoicing regulations.

Key Juleb Benefits:

✅ 100% compliant with ZATCA regulations ✅ Supports both phases of e-invoicing: issuance and full system integration ✅ Easy-to-use interface with minimal training required ✅ Real-time reports for invoice status and pharmacy performance ✅ Automatically issues both standard and simplified invoices ✅ Unified platform for sales, inventory, and accounting ✅ Local customer support available 24/7 ✅ Flexible integration with POS devices, barcode scanners, and printers

6. How to Activate Juleb in Your Pharmacy

1. Book a Free Demo

Start by requesting a free trial to explore the platform and its features.

2. System Setup & Data Configuration

Juleb’s support team will configure the system based on your pharmacy data (customers, products, taxes, etc.)

3. Integration with ZATCA

Once registered on the ZATCA portal, Juleb connects your system using your API credentials.

4. Start Issuing E-Invoices

From day one, you’ll be able to issue certified e-invoices automatically sent to ZATCA.

5. Support & Training

Juleb offers live training sessions and full technical support to help you get the most out of the system.

7. Tips to Ensure Full Compliance

Regularly follow ZATCA’s official updates

Issue invoices instantly at the point of sale

Review invoicing reports daily to catch errors early

Perform regular backups of all data

Keep your software updated to meet the latest changes

8. What Happens If You Don’t Comply?

Non-compliance with the e-invoicing regulations may lead to:

Financial penalties

Suspension of digital government services

Business license cancellation

Issues with VAT return submissions

That’s why full compliance using a trusted solution like Juleb is essential to avoid complications or penalties.

Conclusion

With Saudi Arabia’s push toward full digital transformation, e-invoicing is now a necessity, not an option. Pharmacies, with their high transaction volumes, must adopt smart and secure systems to manage invoicing efficiently.

Your choice of software determines your ease of compliance and operational efficiency. That’s why Juleb stands out — with full ZATCA integration, intuitive use, and ongoing support.

🎯 Book Your Free Demo with Juleb Now!

Don’t waste time on disconnected or non-compliant systems. Try Juleb, the certified solution that gives you everything you need to manage your pharmacy and meet all e-invoicing requirements.

📞 For a free trial or direct booking: Contact the Juleb team today and start your digital journey with confidence.

Start your digital compliance journey today — try "Juleb" and be among the first pharmacies fully aligned with the e-invoicing system! 🚀

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